99%銅ペプチドghk粉末

銅ペプチドghk粉末とは何ですか?

銅ペプチドghkは、グリシル- l-ヒストアシル- l-リシンからなるポリペプチド(トリペプチド-1)と銅イオンが結合した複合体です。その青い外観から、銅ペプチド(copper peptide, ghk-cu)とも呼ばれ、トリペプチド-1銅(tripeptide-1 copper)とも呼ばれる。

1973年、米国ucsfのloren pickart博士は、グリシン、ヒスチジン、リジンからなるヒト由来の低分子ペプチドであるトリペプチド-1 (ghk)をヒト血清から単離した。さらに研究を進めると、トリペプチド-1は非常に強い金属イオンのキレート剤であり、銅イオンと安定な青色複合体である青色銅ペプチド(ghk-cu)を形成することが明らかになった。

銅ペプチドghkは、金属イオンを複合させることができる数少ないペプチド成分の一つで、銅イオンを皮膚の損傷部位に運ぶ担体として、効率的な修復機能を発揮します。また、トリペプチド-1自体は、皮膚に天然に存在するシグナルペプチドで、皮膚のコラーゲンの再生を促し、アンチエイジング効果を発揮します。

銅ペプチド「ghk」は、その優れたスキンケア効果から、古くから多くの有名化粧品メーカーの製品に使用されており、高級品にも多く使用されています。銅ペプチドghk粉末は、その種の他の多くの抗シワ成分よりも優れている、安全で穏やかで、非刺激性です。また、ghkパウダーには、抗酸化、アンチエイジング、抗炎症など、さまざまな効果があり、皮膚に複数の効果をもたらすことができます。

緑泉技術は純度が高く、溶剤残留物がなく、農薬残留物がない99%銅ペプチドghk粉末を供給し、欧州薬局方、米国薬局方、日本薬局方などの国際基準を満たしています。

2000年に設立されたgreen spring technologyは、お客様に自然で安全な有機植物抽出物を提供することに取り組んでいます。当社が提供するすべての製品は、eu ec396、eu 2023/915、および最高の溶剤残渣基準に準拠した、最高の国際的な業界基準に準拠して製造されています。私たちは体系的な品質管理システムを持っており、iso、haccpおよびその他の品質基準に厳密に従って生産を組織しています。halal、kosher、cosmos、brc、ifs、fda、isoなど多くの認証を取得しています。

规格: 

規制:

euの規制に準拠しています。

Benefits:

Anti-Inflammatory, Antioxidant

Scientists investigated the effect of GHK-Cu powder on reactive oxygen species (ROS) and superoxide dismutase SOD activity in LPS-induced cells. The results showed a significant reduction in ROS production after pretreatment with Copper Peptide GHK at 1, 5, and 10 μM. SOD activity was significantly reduced by approximately 19% in LPS-treated cells, and increased to near control levels in cells pretreated with GHK-Cu (1, 5, and 10 μM).

To determine whether GHK-Cu reduced the release of inflammatory cytokines, the levels of TNF-α and IL-6 were confirmed by ELISA. The results showed that cells pretreated with 10 μM Copper Peptide GHK significantly reduced the secretion of these inflammatory molecules. Thus blue copper peptide reduced ROS induced by LPS and increased SOD activity while reducing the release of pro-inflammatory factors to achieve anti-inflammatory and antioxidant effects.

Promoting Hair Growth

Mouse experiments were conducted to observe the effects of the Copper Peptide GHK on hair growth in mice with the alopecia model, while liposomes of blue copper peptide (CHK-Cu) were prepared to promote transdermal absorption and maintain the advantages of maintaining a high concentration of the drug on the skin. The mice were randomly divided into 3 groups of 10 mice each, namely CHK-Cu liposome group, CHK-Cu group, and control group, and the hair growth was observed by different treatments on the hair loss area.

The results showed shorter hair growth time in the CHK-Cu liposome group and CHK-Cu group compared to the control group. light hairs grew all over the depilated area on day 6 in the CHK-Cu liposome group. On day 14, the hairs were more uniform and thicker than those in the CHK-Cu group and the control group, and the hair growth area and length were also better. Observations on the back skin of mice showed that the subcutaneous vascular network was rich and thicker in the CHK-Cu liposome group and CHK-Cu group mice, which was not obvious in the control group. Meanwhile, compared with the control group, the hair follicles in the CHK-Cu liposome group and CHK-Cu group were more fully developed and more numerous. Skin section samples were taken for hair follicle counting, and the number of hair follicles increased in both the GHK-Cu group and the GHK-Cu liposome group of mice compared with the control group, and the difference was statistically significant (P<0.05).

The experiments confirmed that nanoscale liposomes can effectively encapsulate the Copper Peptide GHK powder as well as have a better hair growth effect, which provides ideas for the development of new topical drugs for the treatment of hair loss.

Skin Tissue Repair

Copper Peptide GHK powder is a biologically active regulator naturally occurring on the alpha 2(I) chain of type I collagen in the extracellular matrix (ECM), which is released after skin damage and is an early signal for tissue repair. In addition, endothelial cells express SPARC, a stromal-type cell-secreted glycoprotein, which is degraded to produce GHK and is thought to be a source of serum GHK.

Copper ions are trace elements required for a variety of enzymatic reactions in the human body. The amount of divalent copper ions in human plasma is about 1 μg/mL, with more than 95% present in plasma cuprocyanin and the remaining 5% bound to other molecules (e.g., albumin, histidine, etc.). Due to its high affinity for copper ions, Copper Peptide GHK antagonises other molecules, competes with them for the complexation of copper ions, and acts as a carrier to deliver copper ions to the site of injury, promoting wound healing and tissue repair.

Anti-Aging & Wrinkle Removal

GHK-Cu powder can effectively enhance the functionality of fibroblasts and stimulate fibroblasts to synthesise ECM components such as glycosaminoglycans, proteoglycans, collagen, elastin, etc., to remodel the skin structure. In addition, GHK-Cu also promotes the expression of matrix metalloproteinases MMP-2, MMP-9, and their tissue inhibitors TIMPs. By regulating the activities of MMPs and TIMPs, GHK-Cu can help maintain the balance between matrix decomposition and synthesis, accelerate tissue remodeling, and improve the appearance of aging skin.

Antioxidant and Anti-Inflammatory

Studies have shown that GHK-Cu powder can inhibit inflammation by lowering the levels of acute inflammatory cytokines such as TGF-β and TNF-α. In addition, by providing copper ions to the tissues, GHK-Cu can enhance the activity of superoxide dismutase, thereby inhibiting the generation of reactive oxygen radicals and achieving antioxidant efficacy.

Applications:

In Cosmetics:

Copper Peptide GHK acts on the dermis to promote the synthesis of extracellular matrix, such as collagen and glycosaminoglycans, resulting in thicker, firmer skin. It also stimulates fibroblast synthesis, promotes collagen and elastin neogenesis, increases blood vessel growth and anti-oxidant power, and repairs damage quickly. In high-end skincare products, Complex Copper Peptide GHK Powder can repair DNA damage, dismantle abnormal collagen fibres that form scars and wrinkles, and rebuild normal pattern proteins, with excellent repair and anti-aging effects.