Fermented D Mannose Raw Materials Contribute to Healthy Products

Dmannose is a natural hexose monosaccharide widely found in various fru◆such as citrus, peaches, とapples. It is also a structural component のplant polysaccharides such as pectin and galactomannan. As a low-calorie sweetener, D-mannose is increasingly favoured in the food and health supplement industries due to its refreshing sweetness and natural origin.

Currently, the production of D mannose primarily employs processes such as plant extraction, chemical synthesis, and bioconversion (enzymatic methods). Among these, bioconversion stands out as a more promising green production process due to its advantages of mild reaction conditions, high selectivity, minimal by-products, and environmental friendliness.

This method uses stable sources of fructose or glucose as raw materials, enabling efficient conversion under mild conditions. It is particularly suitable for large-scale production and the preparation of high-purity products, better meeting the global market's growing demands for natural ingredients in terms of quality, safety, and compliance. Green Spring Technology employs advanced biocatalytic enzyme technology to produce high-purity D mannose, with product purity exceeding 99%, and excellent stability and solubility.

We are committed to providing high-quality, compliant, and reliable natural ingredient solutions for customers in the functional food, beverage, and dietary supplement industries, helping them create next-generation health products.

If you are looking for a stable supply of D mannose powder ingredient that are cost-effective and sustainable, please contact Green Spring Technology for product information and technical cooperation solutions.

1   Production Process of D mannose

As a high-value functional ingredient, the production process of D mannose is continuously being optimised and upgraded. Currently, the mainstream production methods include plant extraction, chemical synthesis, and bioconversion. In the past, commercialised D mannose primarily relied on plant extraction or chemical synthesis pathways. However, due to limitations such as raw material supply, high energy consumption, multiple by-products, and complex purification processes, the industry is gradually shifting towards more efficient and environmentally friendly bioconversion technologies.

1.1植物抽出法

The plant extraction method typically uses natural raw materials such as palm kernel and coffee grounds to ex尿管D mannose through hydrolysis, filtration, and purification steps. The advantages of this process include natural raw materials and controllable costs, making it suitable for industrial production at a certain scale. However, the reaction typically requires high temperatures and strong acid-base conditions, resulting in high energy consumption and environmental pressures;Additionally, the availability of plant-based raw materials is susceptible to regional and seasonal fluctuations, posing significant challenges to supply chain stability.

1.2化学合成法

The chemical synthesis method typically uses glucose as the raw material, generating D-mannose through catalytic isomerisation reactions under high-temperature and specific pH conditions. While this method offers stable raw materials, it requires stringent reaction conditions, produces significant by-products, and involves high separation and purification costs, presenting ongoing challenges for industrial application.

1.3 Enzymatic Method

 The enzymatic method uses D-fructose or D-glucose as raw materials and converts them into D-mannose through enzymatic reactions. The enzymatic method (bioconversion method), with its green and efficient characteristics, is emerging as a more promising industrialisation pathway.This method uses fructose or glucose as substrates and, under mild temperature and pH conditions, catalyzes the conversion of D-mannose through specific enzymes (such as D-mannose isomerase). The enzymatic reaction has mild reaction conditions, low energy consumption, environmental friendliness, minimal by-products, and is easier for subsequent separation and purification, making it suitable for large-scale continuous production.

Green Spring Technology employs advanced enzyme engineering technology to optimise the bioconversion process, significantly improving conversion efficiency and product purity. We are committed to providing customers with high-purity, high-quality D mannose raw materials, ensuring batch consistency and supply stability. With our green production process and continuous technological innovation, Green Spring Technology can help customers develop more competitive products in functional foods, health supplements, and other fields, jointly promoting the sustainable development of health ingredients.

2展望

As a highly sought-after natural raw material, D mannose has seen expanding applications in the food and health supplement industries in recent years. With ongoing research and advancements in production technology, enzymatic methods, due to their green, efficient, and sustainable characteristics, have emerged as the preferred route for D mannose production, enabling this natural raw material to unlock its full potential in innovative products.

In the future, with the increasing market demand for functional health ingredients, D mannose is expected to demonstrate broader application prospects in multiple fields such as dietary supplements and functional foods.

Green Spring Technology, as a reliable supplier of D mannose raw materials, produces high-purity D mannose powder using natural fermentation technology. Our products comply with FDA, multiple pharmacopoeia standards, and ISO quality management system requirements, strictly ensuring that impurity and solvent residue levels meet international food safety regulations.

We are committed to providing customers with stable, compliant, and high-quality raw material solutions to support efficient product development and production, accelerating product launch timelines.

For samples, technical documents, or customised services, please contact the Green Spring Technology team. We will provide you with professional and comprehensive supply chain support.

参考:

[1] feng d, shi b, bi f, et al。多嚢胞性卵巣症候群のマーカーとして血清マンノース値の上昇[j]。^ a b c d e f g h『仙台市史』、2019年、10 - 11頁。

[2]藤代は B 女。 準備 コンニャクマンナンの and  its   機能健康機能か[J]。軽工業の科学と技術-  2014年ogy(7) 67−68。

[3] [liu d r .マンノース受容体およびmirna-1260bインガストロリン-睾丸腫瘍の予後的価値に関する研究[d]。『蘭州大学』蘭州大学、2017年。

[4] mex .リウマチ性関節炎ラットにおけるヒト鼻受容体発現および関連抗体に対するシノメニンの効果に関する実験的研究[d]。成都:成都伝統大学 ^『医学』新潮社、2014年。

[5] huang c r, li t p, wang j, et al。表情  血清可溶性マンノース受容体の臨床的意義 pa -  肝細胞癌を伴うtients [j]。安徽医学会誌  1127 7大学、2021年、56()1131−辞退。

6[lu g s, song  b, jin x y .泌尿器の防御機構に関する研究  tract  感染[J]。 誌 of  3 軍事 医療 2000年大学22(11):1116−1118。

[7] yi j y, wang y y, liu x p, et al。コンニャクマンナンの効果  乳癌細胞の増殖とエピルビシンの化学療法感受性について[j]。^「journal of qingdong university: med,2020,57(3):350 - 355」。journal of qingdong university . 2015年3月25日閲覧。

[8 mussatto s i, carneiro l m, silva j p a, et al。使用済みco- ffeeグラウンドからの化学成分および糖抽出に関する研究[j]。2011年炭水化物高分子、83(2):ギター368−374校だった。

[9] [wang b .虚血および再灌流による腸酸化損傷に対する中国ナツメ由来多糖類の化学的特性評価および改善効果[j]。international journal of biological macromolecules,2011,48(3):386−391。