Diosgenin粉

Diosgeninは何ですか?

ジオスゲニン(diosgenin)は、植物によって天然に合成されるステロイドジオスゲニンの一種であり、マメ科やディオスコリア科の植物の塊茎に広く存在する。それはステロイドホルモン薬の合成のための重要な原料です。抗腫瘍、抗炎症、抗酸化など多くの顕著な薬理作用があり、高い薬効がある。

緑色の春には、山芋の塊茎から抽出したディオスゲニン粉末が含まれています。天然のdhea(デヒドロエピアンドロステロン)で、皮膚の表皮細胞の新陳代謝を促進し、皮膚の保湿機能を高め、体質の改善にも役立ちます。

规格: 

法が定め

euの規制に準拠しています。

Benefits:

Antitumor Activity

In vivo and in vitro studies have shown that diosgenin has cytotoxicity to a variety of tumor cells, including breast cancer cells, colon cancer cells, prostate cancer cells, lung cancer cells, gastric cancer cells, Osteosarcoma cells, etc. It can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking cell cycle, and anti-tumor metastasis.

Hepatoprotective Effect

Diosgenin powder can effectively inhibit the cell viability of HSC-T6, LX-2, and primary rat hepatic stellate cells (HSCs), while liver cells are not affected. Diosgenin also has a good protective effect on alcoholic liver injury, which is achieved by reducing oxidative stress, the production of inflammatory cytokines, cell apoptosis, and liver steatosis.

Hypoglycemic Effect

The combination of NPH insulin and diosgenin in the treatment of elderly type 2 diabetes is more effective in reducing blood sugar with good safety, which may be related to the reduction of Glycated hemoglobin formation.

Anti Osteoporosis Effect

Dioscin can promote the proliferation of osteoblasts and inhibit the formation of Osteoclast. Research has shown that after diosgenin treatment of MC3T3-E1 cells, ER- α、 ER- β、 Lrp5 β- The expression of both catenin and Bcl-2 proteins increased, and the ratio of OPG/RANKL increased, depending on the LRP5 pathway, thereby promoting osteoblast proliferation.

Applications:

Pharmaceutical Intermediate:

Diosgenin powder is an important steroidal saponin and an important raw material for Semisynthesis steroidal compounds.