Green Spring Technology's Multi-Specification Epimedium Extract Icariin Helps Customers Develop Products Efficiently

Icariin (ICA) is a natural flavonoid compound derived from the aerial parts of Korean epimedium and heart-leaved epimedium. As the core component of epimedium extracts, it has garnered significant attentiにfor its excellent antioxidant properties. Currently, this compound is increasingly being applied in dietary supplements, functional foods, and nutritional health products, demonstrating vast market potential and application prospects.

Green Spring Technology, as a professional supplier of plant extracts, can consistently provide high-purity Epimedium extract (Icariin ) in various specifications to meet the diverse needs of customers in formula design and new product development. Our products feature consistent quality and excellent solubility, making them easy to incorporate into various dosage forms and health product systems, helping customers effectively shorten R&D cycles and enhance product competitiveness.

1  Properties of Epimedium Extract Icariin

Epimedium extract  Icariin (molecular formula C33H42O16, molecular weight 694.65) is a natural flavonoid compound with excellent solubility. This compound is highly soluble in pyridine and can be dissolved well in common solvents such as methanol, ethanol, and ethyl acetate, demonstrating good formulation adaptability and processing convenience. Its characteristic of darkening in colour upon contact with alkali, along with specific colour reactions (e.g., brown in the Molish reaction, dark green in the FeCl₃ reaction, and pink in the HCl-Mg reaction), provides clear detection criteria for quality control and identification, facilitating the development and quality management of related products.

2  Bioactivity of Epimedium Flavonoids

As a highly regarded natural active ingredient, Epimedium Flavonoids have demonstrated significant potential in the health product sector in recent years. Research indicates that this compound plays a positive role in maintaining immune balance by supporting immune cell proliferation and activity, thereby participating in healthy immune regulation processes.

また、epimedium glycosides show promising applications in neurohealth. Research suggests that this compound helps support the maintenance and self-renewal of neurons and has certain positive effects on cognitive function. Green Spring Technology, leveraging its mature extraction technology, can supply high-purity epimedium extracts in various specifications, providing stable and reliable raw material support for customers in the development of immune-related and neurohealth products, helping enterprises create more competitive, innovative products.

3 Preparation of Epimedium Flavonoids

The efficient preparation and quality control of Epimedium Flavonoids are critical for their commercial application. The Chinese Pharmacopoeia (2010 edition) has explicitly designated Epimedium Flavonoids and Epimedium Flavonoid C as reference standards for content determination, providing an important basis for industry standardisation. Currently, industrial-scale chromatographic techniques are widely applied in the purification of Epimedium extract. For example, the combination of macroporous adsorption resin and high-performance liquid chromatography (HPLC) can achieve the efficient separation of high-purity components such as Epimedium glycoside, Epimedium A, B, and C in two steps, significantly improving production efficiency and product purity.

In terms of extraction processes, 研究have shown that using an alkaline aqueous solution for extraction can significantly increase the total flavonoid yield, with the optimal process achieving an extraction rate of over 97%, while also offering the advantages of simple operation and low cost, making it suitable for large-scale production.

Green Spring Technology, leveraging advanced chromatography technology and process optimisation capabilities, can stably supply various specifications and high-purity Epimedium extracts, strictly adhering to pharmacopoeia standards for quality control, providing reliable raw material support for customer product development and large-scale production.

4展望

Epimedium glycosides, as a highly sought-after natural active ingredient, demonstrate broad application prospects in the health industry. Current research not only focuses on its potential functional value but also continues to explore its mechanisms of action and industrialisation potential. With the application of advanced analytical technologies such as high-resolution mass spectrometry (HPLC-HRMS), the metabolic characteristics of Epimedium have been further clarified, providing strong support for its scientific application in functional foods, dietary supplements, and other fields.

Green Spring Technology, leveraging advanced preparation processes and stringent quality control systems, provides customers with high-purity, multi-specification Epimedium extracts characterised by clear component profiles, batch consistency, and excellent solubility. These extracts can efficiently accommodate the development needs of various dosage forms, including soft capsules, solid beverages, and tablets, effectively helping customers shorten R&D cycles and accelerate product commercialisation.

Looking ahead, we are committed to collaborating with industry partners to advance the innovative application and commercialisation of epimedium glycosides. Please contact Green Spring Technology at helen@greenspringbio.com or WhatsApp: +86 13649243917to request samples and technical information, and join us in creating the next generation of natural health products!

参照

[1]Zhang WJ，Chen  HX、王 zメトロ・カードとデビッド al.Comparative studies  on  葉や茎から抽出物や画分の- tioxidant活性 epimedium koreanum nakai [j]。j food sci tech,2013,50(6): 1122 -1129

[2]Cui L，Zhang ZH，Sun E，et  al.Effectβ- cyclodextrin複雑な-自宅溶存量とタンパクプロダクトオブザ酵素率icariinか[J]。J Nat sci biol med,2013,4(1): 201-206

[3]Wang Qian, Zhang Ling, Mao Haiting, et al. The Chinese herbal medicine Icariside reverses the malignant phenotype and induces differentiation of the liver cancer HepG2.2.15 cell line [J]. World Journal of Gastroenterology, 2007, 15 (19): 2087-2092

[4]Gu Xin, Yang Dandan, Wang Li, et al. Experimental study on the induction of differentiation and reversal of malignant phenotype of the thyroid cancer cell line SW579 by icariin [J]. Progress in Modern General Surgery in China, 2012, 15 (7): 505-509