ジャポニカ(sophora japonica)ケンペロールを抽出する

ソホラジャポニカ抽出物ケンペロールとは?

コンペロールエキスコンペロールは、コンペロールの果実から抽出される有効成分です。黄色の結晶性粉末であり、水に溶け、高温エタノールに可溶、エーテルdmso、および他の有機溶媒。ケンフェロールは、体内から余分なスーパーオキシドラジカルを除去し、dnaや細胞への酸化的損傷を防ぐことができる強力な抗酸化特性を持っています。主に抗がん剤、不妊抑制剤、抗てんかん剤、抗炎症剤、抗酸化剤、抗潰瘍剤として使用されます。

グリーン スプリングテクノロジーは、純度98%にも達する高純度ソホラジャポニカのケンペロールをナノ粒子やリポソマルのナノ粒子などの形で提供しています。ナノ粒子ケンペロールは、水に溶けにくいという問題を解決し、溶解性、安定性、乳化性、抗酸化性に優れ、医薬品原料として利用されてきた。

2000年、グリーンに加入 春 technologyは、高品質の植物抽出物の研究開発に専念している中国の大手バイオテクノロジー企業です。ハラール、コーシャ、cosmos、brc、ifs、fda、iso9001、iso22000など多くの認証を取得しています。体系的な内部品質管理システムを持っており、iso、haccpおよびその他の品質基準に厳密に従ってその生産を組織しています。これらの製品は、eu ec396、eu 2023/915、および最高水準の溶剤残渣基準に準拠しています。

规格: 

法が定め

euの規制に準拠しています。

Benefits:

Antibacterial and Anti-Inflammatory

Studies have shown that kaempferol has good antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The K-Br paper slide method shows that a concentration of 50 mg/tablet can make the circle of inhibition of MRSA up to 8.5 mm, and its antibacterial activity against Vibrio cholerae and Enterococcus faecalis is also very good. In antiviral, kaempferol showed concentration-dependent inhibition at non-cytotoxic concentrations. In anti-inflammation, kaempferol mainly inhibits the expression of inflammatory factors to achieve anti-inflammatory effects.

Contributes to Anticancer

Kaempferol was applied to human gastric cancer cells MGC-803 (in vitro assay), and DAPI staining was observed under a fluorescence microscope, and the results showed that the chromatin of the nucleus was condensed, and the nucleus was dissolved and irregularly shaped. According to the results of the MIT method, it was found that kaempferol could inhibit the proliferation of cancer cells. According to the comet electrophoresis method, most of the cancer cells showed a comet tail shape, which resulted in cellular DNA damage, and finally concluded that kaempferol could inhibit the proliferation of human gastric cancer cells.

Beneficial for Diabetes

Researchers established a mouse model to verify the hypoglycemic and hypolipidemic effects of kaempferol in diabetic mice. Serum triglyceride, total cholesterol, blood glucose, malondialdehyde, glutathione peroxidase, and superoxide dismutase activities were measured in diabetic mice fed with kaempferol and diabetic mice fed with thirst-quenching pills in a control test.

The results showed that kaempferol could effectively reduce serum triglyceride, total cholesterol, blood glucose, and malondialdehyde levels in mice, and significantly increase the activities of serum glutathione peroxidase and superoxide dismutase, with 10 mg/(kg-bw-d) as the optimal dose. Kaempferol can delay the development of diabetes mellitus. The above studies have demonstrated the therapeutic effect of kaempferol on diabetes mellitus.

May Beneficial for Hepatoprotection

In a mouse model of acute liver failure with kaempferol, kaempferol improved hepatic function and pathological changes in mice and inhibited endoplasmic reticulum stress-induced apoptosis in human hepatocyte cell line 7702 cells. It may protect hepatocytes by inhibiting endoplasmic reticulum stress through inhibiting the expression of the endoplasmic reticulum stress-specific apoptotic protein CHOP, which suggests that the use of kaempferol may provide a new intervention for acute liver injury.

Applications:

In Pharmaceutical:

Sophora extract kaempferol is a widely used natural compound with various biological activities such as antioxidant and anti-inflammatory. Due to its unique physicochemical properties, Kaempferol is widely used in various fields. In the field of medicine, kaempferol is mainly used in the treatment of cardiovascular and neurological diseases. In addition, it is used in the preparation of some anticancer drugs and antiparasitic drugs.